Entity Details

Name CD79A
ID P11912
Role substrate
Enzymatic Domains
Ig-like C2-type 33-116
ITAM 177-205
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
FYNCD79ATyr199NLDDCSMyEDISRGLphosphorylation
up-regulates activity		9531288SIGNOR-251153
LYNCD79ATyr188EYEDENLyEGLNLDDphosphorylation
up-regulates activity		9531288SIGNOR-251397
SH2B1CD79A–dephosphorylation
down-regulates activity		32323266SIGNOR-268457
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
FYNphosphorylation
up-regulates
→
CD79A
PTyr199		phosphorylation
up-regulates
→		CD79A9531288SIGNOR-251153
LYNphosphorylation
up-regulates
→
CD79A
PTyr188		phosphorylation
up-regulates
→		CD79A9531288SIGNOR-251397
Regulator Mechanism/Effect Target SIGNOR-ID
FYNphosphorylation
→
up-regulates activity 		CD79ASIGNOR-251153
LYNphosphorylation
→
up-regulates activity 		CD79ASIGNOR-251397
SH2B1dephosphorylation
→
down-regulates activity 		CD79ASIGNOR-268457