| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | PCNA | Tyr211 | QLTFALRyLNFFTKA | phosphorylation up-regulates | 17115032 | SIGNOR-150852 |
| ABL1 | PCNA | Tyr211 | QLTFALRyLNFFTKA | phosphorylation up-regulates activity | 23542172 | SIGNOR-279389 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | phosphorylation up-regulates → | PCNA PTyr211 | phosphorylation up-regulates → | PCNA | 17115032 | SIGNOR-150852 |
| ABL1 | phosphorylation up-regulates → | PCNA PTyr211 | phosphorylation up-regulates → | PCNA | 23542172 | SIGNOR-279389 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EGFR | phosphorylation → up-regulates | PCNA | SIGNOR-150852 |
| ABL1 | phosphorylation → up-regulates activity | PCNA | SIGNOR-279389 |
