Entity Details

Name IGF1R_Tyr250
ID P12004
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
IGF1RPCNATyr250DMGHLKYyLAPKIEDphosphorylation
up-regulates activity		28924044SIGNOR-277252
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
IGF1Rphosphorylation
up-regulates
→
PCNA
PTyr250		phosphorylation
up-regulates
→		PCNA28924044SIGNOR-277252
Regulator Mechanism/Effect Target SIGNOR-ID
IGF1Rphosphorylation
→
up-regulates activity 		PCNASIGNOR-277252