Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPK1	TPR	Thr2137 View in OncoXplorer	EDRTVPStPTLVVPH	phosphorylation up-regulates	18794356	SIGNOR-181022
MAPK1	TPR	Thr2214	GGRSVPTtPLQVAAP	phosphorylation up-regulates	18794356	SIGNOR-181026
MAPK1	TPR	Ser2155 View in OncoXplorer	GFAEAIHsPQVAGVP	phosphorylation up-regulates	18794356	SIGNOR-181014
MAPK1	TPR	Thr2116 View in OncoXplorer	VGRGLQLtPGIGGMQ	phosphorylation up-regulates	18794356	SIGNOR-181018

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK1	phosphorylation up-regulates →	TPR PThr2137	phosphorylation up-regulates →	TPR	18794356	SIGNOR-181022
MAPK1	phosphorylation up-regulates →	TPR PThr2214	phosphorylation up-regulates →	TPR	18794356	SIGNOR-181026
MAPK1	phosphorylation up-regulates →	TPR PSer2155	phosphorylation up-regulates →	TPR	18794356	SIGNOR-181014
MAPK1	phosphorylation up-regulates →	TPR PThr2116	phosphorylation up-regulates →	TPR	18794356	SIGNOR-181018

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPK1	phosphorylation → up-regulates	TPR	SIGNOR-181022
MAPK1	phosphorylation → up-regulates	TPR	SIGNOR-181026
MAPK1	phosphorylation → up-regulates	TPR	SIGNOR-181014
MAPK1	phosphorylation → up-regulates	TPR	SIGNOR-181018