| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | CDH1 | Ser36 | HPGFDAEsYTFTVPR | phosphorylation down-regulates quantity by destabilization | 23972993 | SIGNOR-274051 |
| CDK2 | CDH1 | Ser36 | HPGFDAEsYTFTVPR | phosphorylation down-regulates quantity by destabilization | 23972993 | SIGNOR-274049 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation up-regulates → | CDH1 PSer36 | phosphorylation down-regulates ⊣ | CDH1 | 23972993 | SIGNOR-274051 |
| CDK2 | phosphorylation up-regulates → | CDH1 PSer36 | phosphorylation down-regulates ⊣ | CDH1 | 23972993 | SIGNOR-274049 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation![]() down-regulates quantity by destabilization | CDH1 | SIGNOR-274051 |
| CDK2 | phosphorylation![]() down-regulates quantity by destabilization | CDH1 | SIGNOR-274049 |