Entity Details

Name CyclinA2/CDK2_Thr40
ID P12830
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinA2/CDK2CDH1Thr40DAESYTFtVPRRHLEphosphorylation
down-regulates quantity by destabilization		23972993SIGNOR-274052
CDK2CDH1Thr40DAESYTFtVPRRHLEphosphorylation
down-regulates quantity by destabilization		23972993SIGNOR-274050
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinA2/CDK2phosphorylation
up-regulates
→
CDH1
PThr40		phosphorylation
down-regulates
⊣		CDH123972993SIGNOR-274052
CDK2phosphorylation
up-regulates
→
CDH1
PThr40		phosphorylation
down-regulates
⊣		CDH123972993SIGNOR-274050
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinA2/CDK2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CDH1SIGNOR-274052
CDK2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CDH1SIGNOR-274050