| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | SRC | Ser12 | KSKPKDAsQRRRSLE | phosphorylation unknown | 2996780 | SIGNOR-248893 |
| PPP2CA | SRC | Ser12 | KSKPKDAsQRRRSLE | dephosphorylation down-regulates activity | 18069897 | SIGNOR-247970 |
| PRKCD | SRC | Ser12 | KSKPKDAsQRRRSLE | phosphorylation up-regulates activity | 18069897 | SIGNOR-247974 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | SRC PSer12 | phosphorylation down-regulates ⊣ | SRC | 2996780 | SIGNOR-248893 |
| PPP2CA | dephosphorylation down-regulates ⊣ | SRC PSer12 | dephosphorylation up-regulates → | SRC | 18069897 | SIGNOR-247970 |
| PRKCD | phosphorylation up-regulates → | SRC PSer12 | phosphorylation up-regulates → | SRC | 18069897 | SIGNOR-247974 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation → unknown | SRC | SIGNOR-248893 |
| PPP2CA | dephosphorylation → down-regulates activity | SRC | SIGNOR-247970 |
| PRKCD | phosphorylation → up-regulates activity | SRC | SIGNOR-247974 |
