| Name | BGLF4 |
| ID | P13288 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 1-409 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BGLF4 | IRF3 | Ser123 | DFSQPDTsPDTNGGG | phosphorylation down-regulates activity | 19052084 | SIGNOR-266647 |
| BGLF4 | IRF3 | Ser173 | PCPQPLRsPSLDNPT | phosphorylation down-regulates activity | 19052084 | SIGNOR-266648 |
| BGLF4 | IRF3 | Thr180 | SPSLDNPtPFPNLGP | phosphorylation down-regulates activity | 19052084 | SIGNOR-266649 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BGLF4 | phosphorylation up-regulates → | IRF3 PSer123 | phosphorylation down-regulates ⊣ | IRF3 | 19052084 | SIGNOR-266647 |
| BGLF4 | phosphorylation up-regulates → | IRF3 PSer173 | phosphorylation down-regulates ⊣ | IRF3 | 19052084 | SIGNOR-266648 |
| BGLF4 | phosphorylation up-regulates → | IRF3 PThr180 | phosphorylation down-regulates ⊣ | IRF3 | 19052084 | SIGNOR-266649 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| BGLF4 | phosphorylation → down-regulates activity | IRF3 | SIGNOR-266647 |
| BGLF4 | phosphorylation → down-regulates activity | IRF3 | SIGNOR-266648 |
| BGLF4 | phosphorylation → down-regulates activity | IRF3 | SIGNOR-266649 |