Entity Details

Name CFTR_Ser700
ID P13569
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKG1CFTRSer700
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FGEKRKNsILNPINSphosphorylation
up-regulates activity		1377674SIGNOR-248850
PRKACACFTRSer700
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FGEKRKNsILNPINSphosphorylation
up-regulates activity		1377674SIGNOR-250348
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKG1phosphorylation
up-regulates
→
CFTR
PSer700		phosphorylation
up-regulates
→		CFTR1377674SIGNOR-248850
PRKACAphosphorylation
up-regulates
→
CFTR
PSer700		phosphorylation
up-regulates
→		CFTR1377674SIGNOR-250348
Regulator Mechanism/Effect Target SIGNOR-ID
PRKG1phosphorylation
→
up-regulates activity 		CFTRSIGNOR-248850
PRKACAphosphorylation
→
up-regulates activity 		CFTRSIGNOR-250348