Entity Details

Name PRKACA_Ser737
ID P13569
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LMTK2CFTRSer737EPLERRLsLVPDSEQphosphorylation
down-regulates activity		24727471SIGNOR-278227
AMPKCFTRSer737EPLERRLsLVPDSEQphosphorylation
down-regulates activity		19095655SIGNOR-250350
PRKACACFTRSer737EPLERRLsLVPDSEQphosphorylation
down-regulates activity		19095655SIGNOR-21316
PRKAA1CFTRSer737EPLERRLsLVPDSEQphosphorylation
down-regulates activity		19095655SIGNOR-259858
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LMTK2phosphorylation
up-regulates
→
CFTR
PSer737		phosphorylation
down-regulates
⊣		CFTR24727471SIGNOR-278227
AMPKphosphorylation
up-regulates
→
CFTR
PSer737		phosphorylation
down-regulates
⊣		CFTR19095655SIGNOR-250350
PRKACAphosphorylation
up-regulates
→
CFTR
PSer737		phosphorylation
down-regulates
⊣		CFTR19095655SIGNOR-21316
PRKAA1phosphorylation
up-regulates
→
CFTR
PSer737		phosphorylation
down-regulates
⊣		CFTR19095655SIGNOR-259858
Regulator Mechanism/Effect Target SIGNOR-ID
LMTK2phosphorylation
→
down-regulates activity 		CFTRSIGNOR-278227
AMPKphosphorylation
→
down-regulates activity 		CFTRSIGNOR-250350
PRKACAphosphorylation
→
down-regulates activity 		CFTRSIGNOR-21316
PRKAA1phosphorylation
→
down-regulates activity 		CFTRSIGNOR-259858