Entity Details

Name PRKACA_Ser768
ID P13569
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKACACFTRSer768EPLERRLsLVPDSEQphosphorylation
down-regulates activity		19095655SIGNOR-18141
PRKAA1CFTRSer768LQARRRQsVLNLMTHphosphorylation
down-regulates activity		19095655SIGNOR-259867
AMPKCFTRSer768LQARRRQsVLNLMTHphosphorylation
down-regulates activity		19095655SIGNOR-72708
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKACAphosphorylation
up-regulates
→
CFTR
PSer768		phosphorylation
down-regulates
⊣		CFTR19095655SIGNOR-18141
PRKAA1phosphorylation
up-regulates
→
CFTR
PSer768		phosphorylation
down-regulates
⊣		CFTR19095655SIGNOR-259867
AMPKphosphorylation
up-regulates
→
CFTR
PSer768		phosphorylation
down-regulates
⊣		CFTR19095655SIGNOR-72708
Regulator Mechanism/Effect Target SIGNOR-ID
PRKACAphosphorylation
→
down-regulates activity 		CFTRSIGNOR-18141
PRKAA1phosphorylation
→
down-regulates activity 		CFTRSIGNOR-259867
AMPKphosphorylation
→
down-regulates activity 		CFTRSIGNOR-72708