| Name | EEF2 |
| ID | P13639 |
| Role | substrate |
| Enzymatic Domains |
tr-type G 17-362 PROSITE-ProRule |
View in ![]() |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSK | EEF2 | – | phosphorylation down-regulates quantity | 24648518 | SIGNOR-279698 | |
| EEF2K | EEF2 | Thr57 | RAGETRFtDTRKDEQ | phosphorylation down-regulates | 8386634 | SIGNOR-38552 |
| PPP2CA | EEF2 | Thr59 | GETRFTDtRKDEQER | dephosphorylation up-regulates | 8386634 | SIGNOR-38566 |
| PPP2CA | EEF2 | Thr57 | RAGETRFtDTRKDEQ | dephosphorylation up-regulates | 8386634 | SIGNOR-38561 |
| EEF2K | EEF2 | Thr57 | RAGETRFtDTRKDEQ | phosphorylation down-regulates | 12194824 | SIGNOR-91751 |
| EEF2K | EEF2 | Thr59 | GETRFTDtRKDEQER | phosphorylation down-regulates | 2261989 | SIGNOR-22928 |
| EEF2K | EEF2 | Thr59 | GETRFTDtRKDEQER | phosphorylation down-regulates | 8386634 | SIGNOR-38556 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EEF2K | phosphorylation up-regulates → | EEF2 PThr57 | phosphorylation down-regulates ⊣ | EEF2 | 8386634 | SIGNOR-38552 |
| PPP2CA | dephosphorylation down-regulates ⊣ | EEF2 PThr59 | dephosphorylation down-regulates ⊣ | EEF2 | 8386634 | SIGNOR-38566 |
| PPP2CA | dephosphorylation down-regulates ⊣ | EEF2 PThr57 | dephosphorylation down-regulates ⊣ | EEF2 | 8386634 | SIGNOR-38561 |
| EEF2K | phosphorylation up-regulates → | EEF2 PThr57 | phosphorylation down-regulates ⊣ | EEF2 | 12194824 | SIGNOR-91751 |
| EEF2K | phosphorylation up-regulates → | EEF2 PThr59 | phosphorylation down-regulates ⊣ | EEF2 | 2261989 | SIGNOR-22928 |
| EEF2K | phosphorylation up-regulates → | EEF2 PThr59 | phosphorylation down-regulates ⊣ | EEF2 | 8386634 | SIGNOR-38556 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSK | phosphorylation → down-regulates quantity | EEF2 | SIGNOR-279698 |
| EEF2K | phosphorylation![]() down-regulates | EEF2 | SIGNOR-38552 |
| PPP2CA | dephosphorylation → up-regulates | EEF2 | SIGNOR-38566 |
| PPP2CA | dephosphorylation → up-regulates | EEF2 | SIGNOR-38561 |
| EEF2K | phosphorylation![]() down-regulates | EEF2 | SIGNOR-91751 |
| EEF2K | phosphorylation![]() down-regulates | EEF2 | SIGNOR-22928 |
| EEF2K | phosphorylation![]() down-regulates | EEF2 | SIGNOR-38556 |