| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EEF2K | EEF2 | Thr57 | RAGETRFtDTRKDEQ | phosphorylation down-regulates | 8386634 | SIGNOR-38552 |
| PPP2CA | EEF2 | Thr57 | RAGETRFtDTRKDEQ | dephosphorylation up-regulates | 8386634 | SIGNOR-38561 |
| EEF2K | EEF2 | Thr57 | RAGETRFtDTRKDEQ | phosphorylation down-regulates | 12194824 | SIGNOR-91751 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EEF2K | phosphorylation up-regulates → | EEF2 PThr57 | phosphorylation down-regulates ⊣ | EEF2 | 8386634 | SIGNOR-38552 |
| PPP2CA | dephosphorylation down-regulates ⊣ | EEF2 PThr57 | dephosphorylation down-regulates ⊣ | EEF2 | 8386634 | SIGNOR-38561 |
| EEF2K | phosphorylation up-regulates → | EEF2 PThr57 | phosphorylation down-regulates ⊣ | EEF2 | 12194824 | SIGNOR-91751 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EEF2K | phosphorylation down-regulates | EEF2 | SIGNOR-38552 |
| PPP2CA | dephosphorylation → up-regulates | EEF2 | SIGNOR-38561 |
| EEF2K | phosphorylation down-regulates | EEF2 | SIGNOR-91751 |
