Entity Details

Name GSK3B_Ser641
ID P13807
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BGYS1Ser641YRYPRPAsVPPSPSLphosphorylation
down-regulates activity		6772446SIGNOR-253005
DYRK1AGYS1Ser641YRYPRPAsVPPSPSLphosphorylation
down-regulates activity		14593110SIGNOR-260632
DYRK1BGYS1Ser641YRYPRPAsVPPSPSLphosphorylation
down-regulates activity		14593110SIGNOR-260633
GSK3BGYS1Ser641YRYPRPAsVPPSPSLphosphorylation
down-regulates activity		11427888SIGNOR-251239
GSK3BGYS1Ser641YRYPRPAsVPPSPSLphosphorylation
down-regulates activity		14593110SIGNOR-235793
GSK3AGYS1Ser641YRYPRPAsVPPSPSLphosphorylation
down-regulates		14593110SIGNOR-118927
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
GYS1
PSer641		phosphorylation
down-regulates
⊣		GYS16772446SIGNOR-253005
DYRK1Aphosphorylation
up-regulates
→
GYS1
PSer641		phosphorylation
down-regulates
⊣		GYS114593110SIGNOR-260632
DYRK1Bphosphorylation
up-regulates
→
GYS1
PSer641		phosphorylation
down-regulates
⊣		GYS114593110SIGNOR-260633
GSK3Bphosphorylation
up-regulates
→
GYS1
PSer641		phosphorylation
down-regulates
⊣		GYS111427888SIGNOR-251239
GSK3Bphosphorylation
up-regulates
→
GYS1
PSer641		phosphorylation
down-regulates
⊣		GYS114593110SIGNOR-235793
GSK3Aphosphorylation
up-regulates
→
GYS1
PSer641		phosphorylation
down-regulates
⊣		GYS114593110SIGNOR-118927
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
→
down-regulates activity 		GYS1SIGNOR-253005
DYRK1Aphosphorylation
→
down-regulates activity 		GYS1SIGNOR-260632
DYRK1Bphosphorylation
→
down-regulates activity 		GYS1SIGNOR-260633
GSK3Bphosphorylation
→
down-regulates activity 		GYS1SIGNOR-251239
GSK3Bphosphorylation
→
down-regulates activity 		GYS1SIGNOR-235793
GSK3Aphosphorylation
img/direct_inhibition.png
down-regulates 		GYS1SIGNOR-118927