| Name | GFAP |
| ID | P14136 |
| Role | substrate |
| Enzymatic Domains |
IF rod 69-377 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2A | GFAP | Ser13 | ITSAARRsYVSSGEM | phosphorylation down-regulates activity | 7822264 | SIGNOR-250626 |
| CAMK2A | GFAP | Ser393 | NLQIRETsLDTKSVS | phosphorylation down-regulates activity | 7822264 | SIGNOR-250629 |
| AURKB | GFAP | Thr7 | tSAARRSY | phosphorylation down-regulates activity | 12686604 | SIGNOR-100173 |
| PRKACA | GFAP | Ser38 | LGPGTRLsLARMPPP | phosphorylation down-regulates activity | 2155236 | SIGNOR-249713 |
| CAMK2A | GFAP | Ser38 | LGPGTRLsLARMPPP | phosphorylation down-regulates activity | 7822264 | SIGNOR-250628 |
| AURKB | GFAP | Ser38 | LGPGTRLsLARMPPP | phosphorylation down-regulates activity | 12686604 | SIGNOR-100169 |
| PRKCA | GFAP | Ser13 | ITSAARRsYVSSGEM | phosphorylation down-regulates activity | 2155236 | SIGNOR-248860 |
| PRKCA | GFAP | Ser38 | LGPGTRLsLARMPPP | phosphorylation down-regulates activity | 2155236 | SIGNOR-248862 |
| AURKB | GFAP | Ser13 | ITSAARRsYVSSGEM | phosphorylation down-regulates activity | 12686604 | SIGNOR-100165 |
| ROCK1 | GFAP | Ser13 | ITSAARRsYVSSGEM | phosphorylation down-regulates activity | 12686604 | SIGNOR-100181 |
| PRKACA | GFAP | Thr7 | tSAARRSY | phosphorylation down-regulates activity | 2155236 | SIGNOR-249712 |
| PRKACA | GFAP | Ser13 | ITSAARRsYVSSGEM | phosphorylation down-regulates activity | 2155236 | SIGNOR-249711 |
| ROCK1 | GFAP | Thr7 | tSAARRSY | phosphorylation down-regulates activity | 12686604 | SIGNOR-100192 |
| CAMK2A | GFAP | Ser17 | ARRSYVSsGEMMVGG | phosphorylation down-regulates activity | 7822264 | SIGNOR-250627 |
| ROCK1 | GFAP | Ser38 | LGPGTRLsLARMPPP | phosphorylation down-regulates activity | 12686604 | SIGNOR-100188 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2A | phosphorylation up-regulates → | GFAP PSer13 | phosphorylation down-regulates ⊣ | GFAP | 7822264 | SIGNOR-250626 |
| CAMK2A | phosphorylation up-regulates → | GFAP PSer393 | phosphorylation down-regulates ⊣ | GFAP | 7822264 | SIGNOR-250629 |
| AURKB | phosphorylation up-regulates → | GFAP PThr7 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100173 |
| PRKACA | phosphorylation up-regulates → | GFAP PSer38 | phosphorylation down-regulates ⊣ | GFAP | 2155236 | SIGNOR-249713 |
| CAMK2A | phosphorylation up-regulates → | GFAP PSer38 | phosphorylation down-regulates ⊣ | GFAP | 7822264 | SIGNOR-250628 |
| AURKB | phosphorylation up-regulates → | GFAP PSer38 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100169 |
| PRKCA | phosphorylation up-regulates → | GFAP PSer13 | phosphorylation down-regulates ⊣ | GFAP | 2155236 | SIGNOR-248860 |
| PRKCA | phosphorylation up-regulates → | GFAP PSer38 | phosphorylation down-regulates ⊣ | GFAP | 2155236 | SIGNOR-248862 |
| AURKB | phosphorylation up-regulates → | GFAP PSer13 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100165 |
| ROCK1 | phosphorylation up-regulates → | GFAP PSer13 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100181 |
| PRKACA | phosphorylation up-regulates → | GFAP PThr7 | phosphorylation down-regulates ⊣ | GFAP | 2155236 | SIGNOR-249712 |
| PRKACA | phosphorylation up-regulates → | GFAP PSer13 | phosphorylation down-regulates ⊣ | GFAP | 2155236 | SIGNOR-249711 |
| ROCK1 | phosphorylation up-regulates → | GFAP PThr7 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100192 |
| CAMK2A | phosphorylation up-regulates → | GFAP PSer17 | phosphorylation down-regulates ⊣ | GFAP | 7822264 | SIGNOR-250627 |
| ROCK1 | phosphorylation up-regulates → | GFAP PSer38 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100188 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CAMK2A | phosphorylation → down-regulates activity | GFAP | SIGNOR-250626 |
| CAMK2A | phosphorylation → down-regulates activity | GFAP | SIGNOR-250629 |
| AURKB | phosphorylation → down-regulates activity | GFAP | SIGNOR-100173 |
| PRKACA | phosphorylation → down-regulates activity | GFAP | SIGNOR-249713 |
| CAMK2A | phosphorylation → down-regulates activity | GFAP | SIGNOR-250628 |
| AURKB | phosphorylation → down-regulates activity | GFAP | SIGNOR-100169 |
| PRKCA | phosphorylation → down-regulates activity | GFAP | SIGNOR-248860 |
| PRKCA | phosphorylation → down-regulates activity | GFAP | SIGNOR-248862 |
| AURKB | phosphorylation → down-regulates activity | GFAP | SIGNOR-100165 |
| ROCK1 | phosphorylation → down-regulates activity | GFAP | SIGNOR-100181 |
| PRKACA | phosphorylation → down-regulates activity | GFAP | SIGNOR-249712 |
| PRKACA | phosphorylation → down-regulates activity | GFAP | SIGNOR-249711 |
| ROCK1 | phosphorylation → down-regulates activity | GFAP | SIGNOR-100192 |
| CAMK2A | phosphorylation → down-regulates activity | GFAP | SIGNOR-250627 |
| ROCK1 | phosphorylation → down-regulates activity | GFAP | SIGNOR-100188 |