Entity Details

Name GFAP_Thr7
ID P14136
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKACAGFAPThr7tSAARRSYphosphorylation
down-regulates activity		2155236SIGNOR-249712
ROCK1GFAPThr7tSAARRSYphosphorylation
down-regulates activity		12686604SIGNOR-100192
AURKBGFAPThr7tSAARRSYphosphorylation
down-regulates activity		12686604SIGNOR-100173
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKACAphosphorylation
up-regulates
→
GFAP
PThr7		phosphorylation
down-regulates
⊣		GFAP2155236SIGNOR-249712
ROCK1phosphorylation
up-regulates
→
GFAP
PThr7		phosphorylation
down-regulates
⊣		GFAP12686604SIGNOR-100192
AURKBphosphorylation
up-regulates
→
GFAP
PThr7		phosphorylation
down-regulates
⊣		GFAP12686604SIGNOR-100173
Regulator Mechanism/Effect Target SIGNOR-ID
PRKACAphosphorylation
→
down-regulates activity 		GFAPSIGNOR-249712
ROCK1phosphorylation
→
down-regulates activity 		GFAPSIGNOR-100192
AURKBphosphorylation
→
down-regulates activity 		GFAPSIGNOR-100173