Entity Details

Name PRKACA_Ser13
ID P14136
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ROCK1GFAPSer13ITSAARRsYVSSGEMphosphorylation
down-regulates activity		12686604SIGNOR-100181
PRKACAGFAPSer13ITSAARRsYVSSGEMphosphorylation
down-regulates activity		2155236SIGNOR-249711
CAMK2AGFAPSer13ITSAARRsYVSSGEMphosphorylation
down-regulates activity		7822264SIGNOR-250626
PRKCAGFAPSer13ITSAARRsYVSSGEMphosphorylation
down-regulates activity		2155236SIGNOR-248860
AURKBGFAPSer13ITSAARRsYVSSGEMphosphorylation
down-regulates activity		12686604SIGNOR-100165
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ROCK1phosphorylation
up-regulates
→
GFAP
PSer13		phosphorylation
down-regulates
⊣		GFAP12686604SIGNOR-100181
PRKACAphosphorylation
up-regulates
→
GFAP
PSer13		phosphorylation
down-regulates
⊣		GFAP2155236SIGNOR-249711
CAMK2Aphosphorylation
up-regulates
→
GFAP
PSer13		phosphorylation
down-regulates
⊣		GFAP7822264SIGNOR-250626
PRKCAphosphorylation
up-regulates
→
GFAP
PSer13		phosphorylation
down-regulates
⊣		GFAP2155236SIGNOR-248860
AURKBphosphorylation
up-regulates
→
GFAP
PSer13		phosphorylation
down-regulates
⊣		GFAP12686604SIGNOR-100165
Regulator Mechanism/Effect Target SIGNOR-ID
ROCK1phosphorylation
→
down-regulates activity 		GFAPSIGNOR-100181
PRKACAphosphorylation
→
down-regulates activity 		GFAPSIGNOR-249711
CAMK2Aphosphorylation
→
down-regulates activity 		GFAPSIGNOR-250626
PRKCAphosphorylation
→
down-regulates activity 		GFAPSIGNOR-248860
AURKBphosphorylation
→
down-regulates activity 		GFAPSIGNOR-100165