| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKB | GFAP | Thr7 | tSAARRSY | phosphorylation down-regulates activity | 12686604 | SIGNOR-100173 |
| PRKACA | GFAP | Thr7 | tSAARRSY | phosphorylation down-regulates activity | 2155236 | SIGNOR-249712 |
| ROCK1 | GFAP | Thr7 | tSAARRSY | phosphorylation down-regulates activity | 12686604 | SIGNOR-100192 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKB | phosphorylation up-regulates → | GFAP PThr7 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100173 |
| PRKACA | phosphorylation up-regulates → | GFAP PThr7 | phosphorylation down-regulates ⊣ | GFAP | 2155236 | SIGNOR-249712 |
| ROCK1 | phosphorylation up-regulates → | GFAP PThr7 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100192 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AURKB | phosphorylation → down-regulates activity | GFAP | SIGNOR-100173 |
| PRKACA | phosphorylation → down-regulates activity | GFAP | SIGNOR-249712 |
| ROCK1 | phosphorylation → down-regulates activity | GFAP | SIGNOR-100192 |