Entity Details

Name ROCK1_Ser38
ID P14136
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AURKBGFAPSer38LGPGTRLsLARMPPPphosphorylation
down-regulates activity		12686604SIGNOR-100169
PRKCAGFAPSer38LGPGTRLsLARMPPPphosphorylation
down-regulates activity		2155236SIGNOR-248862
ROCK1GFAPSer38LGPGTRLsLARMPPPphosphorylation
down-regulates activity		12686604SIGNOR-100188
CAMK2AGFAPSer38LGPGTRLsLARMPPPphosphorylation
down-regulates activity		7822264SIGNOR-250628
PRKACAGFAPSer38LGPGTRLsLARMPPPphosphorylation
down-regulates activity		2155236SIGNOR-249713
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AURKBphosphorylation
up-regulates
→
GFAP
PSer38		phosphorylation
down-regulates
⊣		GFAP12686604SIGNOR-100169
PRKCAphosphorylation
up-regulates
→
GFAP
PSer38		phosphorylation
down-regulates
⊣		GFAP2155236SIGNOR-248862
ROCK1phosphorylation
up-regulates
→
GFAP
PSer38		phosphorylation
down-regulates
⊣		GFAP12686604SIGNOR-100188
CAMK2Aphosphorylation
up-regulates
→
GFAP
PSer38		phosphorylation
down-regulates
⊣		GFAP7822264SIGNOR-250628
PRKACAphosphorylation
up-regulates
→
GFAP
PSer38		phosphorylation
down-regulates
⊣		GFAP2155236SIGNOR-249713
Regulator Mechanism/Effect Target SIGNOR-ID
AURKBphosphorylation
→
down-regulates activity 		GFAPSIGNOR-100169
PRKCAphosphorylation
→
down-regulates activity 		GFAPSIGNOR-248862
ROCK1phosphorylation
→
down-regulates activity 		GFAPSIGNOR-100188
CAMK2Aphosphorylation
→
down-regulates activity 		GFAPSIGNOR-250628
PRKACAphosphorylation
→
down-regulates activity 		GFAPSIGNOR-249713