Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
LYN	HCLS1	Tyr397 View in OncoXplorer	EDEPEGDyEEVLEPE	phosphorylation up-regulates activity	9104825	SIGNOR-251401
SYK	HCLS1	Tyr397 View in OncoXplorer	EDEPEGDyEEVLEPE	phosphorylation up-regulates	9104825	SIGNOR-47342

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
LYN	phosphorylation up-regulates →	HCLS1 PTyr397	phosphorylation up-regulates →	HCLS1	9104825	SIGNOR-251401
SYK	phosphorylation up-regulates →	HCLS1 PTyr397	phosphorylation up-regulates →	HCLS1	9104825	SIGNOR-47342

Regulator	Mechanism/Effect	Target	SIGNOR-ID
LYN	phosphorylation → up-regulates activity	HCLS1	SIGNOR-251401
SYK	phosphorylation → up-regulates	HCLS1	SIGNOR-47342