Entity Details

Name DRD2
ID P14416
Role substrate
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK5DRD2Ser321GLHSTPDsPAKPEKNphosphorylation
down-regulates activity		24391960SIGNOR-259401
GRK6DRD2–phosphorylation
down-regulates activity		26694375SIGNOR-279046
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK5phosphorylation
up-regulates
→
DRD2
PSer321		phosphorylation
down-regulates
⊣		DRD224391960SIGNOR-259401
Regulator Mechanism/Effect Target SIGNOR-ID
CDK5phosphorylation
→
down-regulates activity 		DRD2SIGNOR-259401
GRK6phosphorylation
→
down-regulates activity 		DRD2SIGNOR-279046