Entity Details

Name PKM
ID P14618
Role kinase
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PKMSTAT3Tyr705DPGSAAPyLKTKFICphosphorylation
up-regulates		22306293SIGNOR-195766
PKMSTAT3Tyr705DPGSAAPyLKTKFICphosphorylation
up-regulates activity		22306293SIGNOR-267716
PKMRBBP8Thr126ELMNERNtLQEENKKphosphorylation
up-regulates activity		30297868SIGNOR-277413
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PKMphosphorylation
up-regulates
→
STAT3
PTyr705		phosphorylation
up-regulates
→		STAT322306293SIGNOR-195766
PKMphosphorylation
up-regulates
→
STAT3
PTyr705		phosphorylation
up-regulates
→		STAT322306293SIGNOR-267716
PKMphosphorylation
up-regulates
→
RBBP8
PThr126		phosphorylation
up-regulates
→		RBBP830297868SIGNOR-277413
Regulator Mechanism/Effect Target SIGNOR-ID
PKMphosphorylation
→
up-regulates 		STAT3SIGNOR-195766
PKMphosphorylation
→
up-regulates activity 		STAT3SIGNOR-267716
PKMphosphorylation
→
up-regulates activity 		RBBP8SIGNOR-277413