| Name | IL1R1 |
| ID | P14778 |
| Role | kinase |
| Enzymatic Domains |
Ig-like C2-type 1 23-110
Ig-like C2-type 2 118-210
Ig-like C2-type 3 226-328
TIR 383-538 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IL1R1 | MAPK8 | – | phosphorylation up-regulates activity | 9625767 | SIGNOR-249513 | |
| IL1R1 | MAPK9 | – | phosphorylation up-regulates activity | 9625767 | SIGNOR-249514 | |
| IL1R1 | MAPK10 | – | phosphorylation up-regulates activity | 9625767 | SIGNOR-249515 | |
| IL1R1 | JNK | – | phosphorylation up-regulates activity | 9625767 | SIGNOR-269883 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| IL1R1 | phosphorylation → up-regulates activity | MAPK8 | SIGNOR-249513 |
| IL1R1 | phosphorylation → up-regulates activity | MAPK9 | SIGNOR-249514 |
| IL1R1 | phosphorylation → up-regulates activity | MAPK10 | SIGNOR-249515 |
| IL1R1 | phosphorylation → up-regulates activity | JNK | SIGNOR-269883 |