Entity Details

Name IFNGR1
ID P15260
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
JAK2IFNGR1–phosphorylation
up-regulates activity		23898330SIGNOR-249490
JAK1IFNGR1Tyr457KAPTSFGyDKPHVLVphosphorylation
up-regulates		7615558SIGNOR-29866
JAK1IFNGR1–phosphorylation
up-regulates activity		19041276SIGNOR-249488
GSK3BIFNGR1–phosphorylation
up-regulates quantity by stabilization		28883123SIGNOR-279720
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
JAK1phosphorylation
up-regulates
→
IFNGR1
PTyr457		phosphorylation
up-regulates
→		IFNGR17615558SIGNOR-29866
Regulator Mechanism/Effect Target SIGNOR-ID
JAK2phosphorylation
→
up-regulates activity 		IFNGR1SIGNOR-249490
JAK1phosphorylation
→
up-regulates 		IFNGR1SIGNOR-29866
JAK1phosphorylation
→
up-regulates activity 		IFNGR1SIGNOR-249488
GSK3Bphosphorylation
→
up-regulates quantity by stabilization 		IFNGR1SIGNOR-279720