| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | NME1 | Ser120 | GRNIIHGsDSVESAE | phosphorylation up-regulates | 18234856 | SIGNOR-216825 |
| CDK1 | NME1 | Ser120 | GRNIIHGsDSVESAE | phosphorylation up-regulates | 18234856 | SIGNOR-160493 |
| NME1 | NME1 | Ser120 | GRNIIHGsDSVESAE | phosphorylation unknown | 8810265 | SIGNOR-250300 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | NME1 PSer120 | phosphorylation up-regulates → | NME1 | 18234856 | SIGNOR-216825 |
| CDK1 | phosphorylation up-regulates → | NME1 PSer120 | phosphorylation up-regulates → | NME1 | 18234856 | SIGNOR-160493 |
| NME1 | phosphorylation up-regulates → | NME1 PSer120 | phosphorylation down-regulates ⊣ | NME1 | 8810265 | SIGNOR-250300 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation → up-regulates | NME1 | SIGNOR-216825 |
| CDK1 | phosphorylation → up-regulates | NME1 | SIGNOR-160493 |
| NME1 | phosphorylation → unknown | NME1 | SIGNOR-250300 |
