| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | RPA2 | Thr21 | YGGAGGYtQSPGGFG | phosphorylation unknown | 14872059 | SIGNOR-121865 |
| PRKDC | RPA2 | Thr21 | YGGAGGYtQSPGGFG | phosphorylation unknown | 14872059 | SIGNOR-121873 |
| ATM | RPA2 | Thr21 | YGGAGGYtQSPGGFG | phosphorylation up-regulates | 14872059 | SIGNOR-121861 |
| PRKDC | RPA2 | Thr21 | YGGAGGYtQSPGGFG | phosphorylation unknown | 9139719 | SIGNOR-248972 |
| PRKDC | RPA2 | Thr21 | YGGAGGYtQSPGGFG | phosphorylation up-regulates | 14872059 | SIGNOR-121869 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | phosphorylation up-regulates → | RPA2 PThr21 | phosphorylation down-regulates ⊣ | RPA2 | 14872059 | SIGNOR-121865 |
| PRKDC | phosphorylation up-regulates → | RPA2 PThr21 | phosphorylation down-regulates ⊣ | RPA2 | 14872059 | SIGNOR-121873 |
| ATM | phosphorylation up-regulates → | RPA2 PThr21 | phosphorylation up-regulates → | RPA2 | 14872059 | SIGNOR-121861 |
| PRKDC | phosphorylation up-regulates → | RPA2 PThr21 | phosphorylation down-regulates ⊣ | RPA2 | 9139719 | SIGNOR-248972 |
| PRKDC | phosphorylation up-regulates → | RPA2 PThr21 | phosphorylation up-regulates → | RPA2 | 14872059 | SIGNOR-121869 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATM | phosphorylation → unknown | RPA2 | SIGNOR-121865 |
| PRKDC | phosphorylation → unknown | RPA2 | SIGNOR-121873 |
| ATM | phosphorylation → up-regulates | RPA2 | SIGNOR-121861 |
| PRKDC | phosphorylation → unknown | RPA2 | SIGNOR-248972 |
| PRKDC | phosphorylation → up-regulates | RPA2 | SIGNOR-121869 |
