Entity Details

Name EGFR_Tyr1229
ID P15941
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
EGFRMUC1Tyr1229SSTDRSPyEKVSAGNphosphorylation
up-regulates activity		11483589SIGNOR-109538
LCKMUC1Tyr1229SSTDRSPyEKVSAGNphosphorylation
up-regulates activity		14766232SIGNOR-247058
SRCMUC1Tyr1229SSTDRSPyEKVSAGNphosphorylation
up-regulates		11152665SIGNOR-85938
LCKMUC1Tyr1229SSTDRSPyEKVSAGNphosphorylation
up-regulates activity		14766232SIGNOR-249358
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EGFRphosphorylation
up-regulates
→
MUC1
PTyr1229		phosphorylation
up-regulates
→		MUC111483589SIGNOR-109538
LCKphosphorylation
up-regulates
→
MUC1
PTyr1229		phosphorylation
up-regulates
→		MUC114766232SIGNOR-247058
SRCphosphorylation
up-regulates
→
MUC1
PTyr1229		phosphorylation
up-regulates
→		MUC111152665SIGNOR-85938
LCKphosphorylation
up-regulates
→
MUC1
PTyr1229		phosphorylation
up-regulates
→		MUC114766232SIGNOR-249358
Regulator Mechanism/Effect Target SIGNOR-ID
EGFRphosphorylation
→
up-regulates activity 		MUC1SIGNOR-109538
LCKphosphorylation
→
up-regulates activity 		MUC1SIGNOR-247058
SRCphosphorylation
→
up-regulates 		MUC1SIGNOR-85938
LCKphosphorylation
→
up-regulates activity 		MUC1SIGNOR-249358