| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK5 | GATA1 | Ser187 | LNSAAYSsPKLRGTL | phosphorylation up-regulates activity | 25726523 | SIGNOR-275656 |
| AKT1 | GATA1 | Ser310 | QTRNRKAsGKGKKKR | phosphorylation up-regulates | 16107690 | SIGNOR-139782 |
| PAK5 | GATA1 | Ser187 | LNSAAYSsPKLRGTL | phosphorylation up-regulates activity | 25726523 | SIGNOR-278297 |
| AKT | GATA1 | Ser310 | QTRNRKAsGKGKKKR | phosphorylation up-regulates | 16107690 | SIGNOR-244267 |
| PAK5 | GATA1 | Ser161 | SSLPVPNsAYGGPDF | phosphorylation up-regulates activity | 25726523 | SIGNOR-275655 |
| PAK5 | GATA1 | Ser161 | SSLPVPNsAYGGPDF | phosphorylation up-regulates activity | 25726523 | SIGNOR-278296 |
| PAK6 | GATA1 | Ser187 | LNSAAYSsPKLRGTL | phosphorylation up-regulates activity | 25726523 | SIGNOR-278415 |
| PAK6 | GATA1 | Ser161 | SSLPVPNsAYGGPDF | phosphorylation up-regulates activity | 25726523 | SIGNOR-278416 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK5 | phosphorylation up-regulates → | GATA1 PSer187 | phosphorylation up-regulates → | GATA1 | 25726523 | SIGNOR-275656 |
| AKT1 | phosphorylation up-regulates → | GATA1 PSer310 | phosphorylation up-regulates → | GATA1 | 16107690 | SIGNOR-139782 |
| PAK5 | phosphorylation up-regulates → | GATA1 PSer187 | phosphorylation up-regulates → | GATA1 | 25726523 | SIGNOR-278297 |
| AKT | phosphorylation up-regulates → | GATA1 PSer310 | phosphorylation up-regulates → | GATA1 | 16107690 | SIGNOR-244267 |
| PAK5 | phosphorylation up-regulates → | GATA1 PSer161 | phosphorylation up-regulates → | GATA1 | 25726523 | SIGNOR-275655 |
| PAK5 | phosphorylation up-regulates → | GATA1 PSer161 | phosphorylation up-regulates → | GATA1 | 25726523 | SIGNOR-278296 |
| PAK6 | phosphorylation up-regulates → | GATA1 PSer187 | phosphorylation up-regulates → | GATA1 | 25726523 | SIGNOR-278415 |
| PAK6 | phosphorylation up-regulates → | GATA1 PSer161 | phosphorylation up-regulates → | GATA1 | 25726523 | SIGNOR-278416 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK5 | phosphorylation → up-regulates activity | GATA1 | SIGNOR-275656 |
| AKT1 | phosphorylation → up-regulates | GATA1 | SIGNOR-139782 |
| PAK5 | phosphorylation → up-regulates activity | GATA1 | SIGNOR-278297 |
| AKT | phosphorylation → up-regulates | GATA1 | SIGNOR-244267 |
| PAK5 | phosphorylation → up-regulates activity | GATA1 | SIGNOR-275655 |
| PAK5 | phosphorylation → up-regulates activity | GATA1 | SIGNOR-278296 |
| PAK6 | phosphorylation → up-regulates activity | GATA1 | SIGNOR-278415 |
| PAK6 | phosphorylation → up-regulates activity | GATA1 | SIGNOR-278416 |
