| Name | NCK1 |
| ID | P16333 |
| Role | substrate |
| Enzymatic Domains |
SH3 1 2-61 PROSITE-ProRule
SH3 2 106-165 PROSITE-ProRule
SH3 3 190-252 PROSITE-ProRule
SH2 282-376 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EIF2AK2 | NCK1 | – | phosphorylation down-regulates activity | 18835251 | SIGNOR-279039 | |
| ABL1 | NCK1 | Tyr105 | VDPGERLyDLNMPAY | phosphorylation up-regulates | 22327338 | SIGNOR-196043 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | phosphorylation up-regulates → | NCK1 PTyr105 | phosphorylation up-regulates → | NCK1 | 22327338 | SIGNOR-196043 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EIF2AK2 | phosphorylation → down-regulates activity | NCK1 | SIGNOR-279039 |
| ABL1 | phosphorylation → up-regulates | NCK1 | SIGNOR-196043 |