Entity Details

Name CTLA4
ID P16410
Role substrate
Enzymatic Domains
Ig-like V-type 39-140
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
FYNCTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization		9973379SIGNOR-251161
JAK2CTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization		10842319SIGNOR-251346
TXKCTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization		9813138SIGNOR-61624
LCKCTLA4Tyr218CEKQFQPyFIPINphosphorylation
unknown		9973379SIGNOR-251371
LCKCTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization		9973379SIGNOR-251370
FYNCTLA4Tyr218CEKQFQPyFIPINphosphorylation
unknown		9973379SIGNOR-251160
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
FYNphosphorylation
up-regulates
→
CTLA4
PTyr201		phosphorylation
up-regulates
→		CTLA49973379SIGNOR-251161
JAK2phosphorylation
up-regulates
→
CTLA4
PTyr201		phosphorylation
up-regulates
→		CTLA410842319SIGNOR-251346
TXKphosphorylation
up-regulates
→
CTLA4
PTyr201		phosphorylation
up-regulates
→		CTLA49813138SIGNOR-61624
LCKphosphorylation
up-regulates
→
CTLA4
PTyr218		phosphorylation
down-regulates
⊣		CTLA49973379SIGNOR-251371
LCKphosphorylation
up-regulates
→
CTLA4
PTyr201		phosphorylation
up-regulates
→		CTLA49973379SIGNOR-251370
FYNphosphorylation
up-regulates
→
CTLA4
PTyr218		phosphorylation
down-regulates
⊣		CTLA49973379SIGNOR-251160
Regulator Mechanism/Effect Target SIGNOR-ID
FYNphosphorylation
→
up-regulates quantity by stabilization 		CTLA4SIGNOR-251161
JAK2phosphorylation
→
up-regulates quantity by stabilization 		CTLA4SIGNOR-251346
TXKphosphorylation
→
up-regulates quantity by stabilization 		CTLA4SIGNOR-61624
LCKphosphorylation
→
unknown 		CTLA4SIGNOR-251371
LCKphosphorylation
→
up-regulates quantity by stabilization 		CTLA4SIGNOR-251370
FYNphosphorylation
→
unknown 		CTLA4SIGNOR-251160