Entity Details

Name JAK2_Tyr201
ID P16410
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TXKCTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization		9813138SIGNOR-61624
JAK2CTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization		10842319SIGNOR-251346
LCKCTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization		9973379SIGNOR-251370
FYNCTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization		9973379SIGNOR-251161
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TXKphosphorylation
up-regulates
→
CTLA4
PTyr201		phosphorylation
up-regulates
→		CTLA49813138SIGNOR-61624
JAK2phosphorylation
up-regulates
→
CTLA4
PTyr201		phosphorylation
up-regulates
→		CTLA410842319SIGNOR-251346
LCKphosphorylation
up-regulates
→
CTLA4
PTyr201		phosphorylation
up-regulates
→		CTLA49973379SIGNOR-251370
FYNphosphorylation
up-regulates
→
CTLA4
PTyr201		phosphorylation
up-regulates
→		CTLA49973379SIGNOR-251161
Regulator Mechanism/Effect Target SIGNOR-ID
TXKphosphorylation
→
up-regulates quantity by stabilization 		CTLA4SIGNOR-61624
JAK2phosphorylation
→
up-regulates quantity by stabilization 		CTLA4SIGNOR-251346
LCKphosphorylation
→
up-regulates quantity by stabilization 		CTLA4SIGNOR-251370
FYNphosphorylation
→
up-regulates quantity by stabilization 		CTLA4SIGNOR-251161