Entity Details

Name FER
ID P16591
Role substrate
Enzymatic Domains
F-BAR 1-259
PROSITE-ProRule
SH2 460-550
PROSITE-ProRule
Protein kinase 563-816
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
FERFERTyr714RQEDGGVySSSGLKQphosphorylation
up-regulates activity		19159681SIGNOR-276236
HSP90AA1FERTyr714RQEDGGVySSSGLKQphosphorylation
down-regulates activity		19159681SIGNOR-277818
FERFERTyr714RQEDGGVySSSGLKQphosphorylation
up-regulates activity		10998246SIGNOR-251133
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
FERphosphorylation
up-regulates
→
FER
PTyr714		phosphorylation
up-regulates
→		FER19159681SIGNOR-276236
HSP90AA1phosphorylation
up-regulates
→
FER
PTyr714		phosphorylation
down-regulates
⊣		FER19159681SIGNOR-277818
FERphosphorylation
up-regulates
→
FER
PTyr714		phosphorylation
up-regulates
→		FER10998246SIGNOR-251133
Regulator Mechanism/Effect Target SIGNOR-ID
FERphosphorylation
→
up-regulates activity 		FERSIGNOR-276236
HSP90AA1phosphorylation
→
down-regulates activity 		FERSIGNOR-277818
FERphosphorylation
→
up-regulates activity 		FERSIGNOR-251133