Entity Details

Name BTK_Tyr759
ID P16885
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
HCKPLCG2Tyr759LYDVSRMyVDPSEINphosphorylation
up-regulates activity		7682059SIGNOR-249364
FYNPLCG2Tyr759LYDVSRMyVDPSEINphosphorylation
up-regulates activity		7682059SIGNOR-249340
BTKPLCG2Tyr759LYDVSRMyVDPSEINphosphorylation
up-regulates activity		11507089SIGNOR-109758
LCKPLCG2Tyr759LYDVSRMyVDPSEINphosphorylation
up-regulates		12181444SIGNOR-91477
BTKPLCG2Tyr759LYDVSRMyVDPSEINphosphorylation
up-regulates		11606584SIGNOR-111073
LYNPLCG2Tyr759LYDVSRMyVDPSEINphosphorylation
up-regulates activity		7682059SIGNOR-249384
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
HCKphosphorylation
up-regulates
→
PLCG2
PTyr759		phosphorylation
up-regulates
→		PLCG27682059SIGNOR-249364
FYNphosphorylation
up-regulates
→
PLCG2
PTyr759		phosphorylation
up-regulates
→		PLCG27682059SIGNOR-249340
BTKphosphorylation
up-regulates
→
PLCG2
PTyr759		phosphorylation
up-regulates
→		PLCG211507089SIGNOR-109758
LCKphosphorylation
up-regulates
→
PLCG2
PTyr759		phosphorylation
up-regulates
→		PLCG212181444SIGNOR-91477
BTKphosphorylation
up-regulates
→
PLCG2
PTyr759		phosphorylation
up-regulates
→		PLCG211606584SIGNOR-111073
LYNphosphorylation
up-regulates
→
PLCG2
PTyr759		phosphorylation
up-regulates
→		PLCG27682059SIGNOR-249384
Regulator Mechanism/Effect Target SIGNOR-ID
HCKphosphorylation
→
up-regulates activity 		PLCG2SIGNOR-249364
FYNphosphorylation
→
up-regulates activity 		PLCG2SIGNOR-249340
BTKphosphorylation
→
up-regulates activity 		PLCG2SIGNOR-109758
LCKphosphorylation
→
up-regulates 		PLCG2SIGNOR-91477
BTKphosphorylation
→
up-regulates 		PLCG2SIGNOR-111073
LYNphosphorylation
→
up-regulates activity 		PLCG2SIGNOR-249384