| Name | STMN1 |
| ID | P16949 |
| Role | substrate |
| Enzymatic Domains |
SLD 4-145 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2A | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 16982419 | SIGNOR-149640 |
| CDK1 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation up-regulates activity | 8125092 | SIGNOR-279802 |
| PAK4 | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates activity | 20805321 | SIGNOR-280058 |
| PRKACA | STMN1 | Ser63 | AAEERRKsHEAEVLK | phosphorylation down-regulates | 8376365 | SIGNOR-38322 |
| MAPK13 | STMN1 | Ser25 | QAFELILsPRSKESV | phosphorylation down-regulates | 8325880 | SIGNOR-37848 |
| CDK5 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 20630875 | SIGNOR-166682 |
| CAMK4 | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 7925472 | SIGNOR-34743 |
| PRKCB | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 7637391 | SIGNOR-30357 |
| UHMK1 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 19033656 | SIGNOR-182489 |
| PRKACA | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 8125092 | SIGNOR-36370 |
| ERK1/2 | STMN1 | – | phosphorylation down-regulates activity | 9731215 | SIGNOR-270182 | |
| PAK1 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 10913145 | SIGNOR-79955 |
| PAK1 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 19162178 | SIGNOR-183503 |
| MAPK1 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 20630875 | SIGNOR-166686 |
| MAPK3 | STMN1 | Ser25 | QAFELILsPRSKESV | phosphorylation down-regulates activity | 9731215 | SIGNOR-249482 |
| CDK1 | STMN1 | Ser25 | QAFELILsPRSKESV | phosphorylation up-regulates activity | 8125092 | SIGNOR-279803 |
| MAPK8 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 20630875 | SIGNOR-166694 |
| PAK1 | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 14645234 | SIGNOR-119483 |
| MAPK3 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates activity | 9731215 | SIGNOR-249483 |
| Gbeta | STMN1 | – | phosphorylation down-regulates activity | 9731215 | SIGNOR-270082 | |
| MAPK13 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 8325880 | SIGNOR-25826 |
| PRKCB | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 9271428 | SIGNOR-50598 |
| CAMK2A | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 9686569 | SIGNOR-59354 |
| PRKCB | STMN1 | Ser25 | QAFELILsPRSKESV | phosphorylation down-regulates | 7637391 | SIGNOR-30353 |
| MAPK10 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 20630875 | SIGNOR-166690 |
| MAPK13 | STMN1 | Ser25 | QAFELILsPRSKESV | phosphorylation down-regulates | 8125092 | SIGNOR-36362 |
| PRKCB | STMN1 | Ser25 | QAFELILsPRSKESV | phosphorylation down-regulates | 9271428 | SIGNOR-50594 |
| CAMK2B | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 9686569 | SIGNOR-59358 |
| PRKACA | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 8376365 | SIGNOR-38318 |
| PRKACA | STMN1 | Ser63 | AAEERRKsHEAEVLK | phosphorylation down-regulates | 8125092 | SIGNOR-36374 |
| AURKA | STMN1 | – | phosphorylation down-regulates activity | 33037191 | SIGNOR-278913 | |
| JNK | STMN1 | – | phosphorylation down-regulates | 20630875 | SIGNOR-269982 | |
| MAPK9 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 20630875 | SIGNOR-166698 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2A | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 16982419 | SIGNOR-149640 |
| CDK1 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation up-regulates → | STMN1 | 8125092 | SIGNOR-279802 |
| PAK4 | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 20805321 | SIGNOR-280058 |
| PRKACA | phosphorylation up-regulates → | STMN1 PSer63 | phosphorylation down-regulates ⊣ | STMN1 | 8376365 | SIGNOR-38322 |
| MAPK13 | phosphorylation up-regulates → | STMN1 PSer25 | phosphorylation down-regulates ⊣ | STMN1 | 8325880 | SIGNOR-37848 |
| CDK5 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 20630875 | SIGNOR-166682 |
| CAMK4 | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 7925472 | SIGNOR-34743 |
| PRKCB | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 7637391 | SIGNOR-30357 |
| UHMK1 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 19033656 | SIGNOR-182489 |
| PRKACA | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 8125092 | SIGNOR-36370 |
| PAK1 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 10913145 | SIGNOR-79955 |
| PAK1 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 19162178 | SIGNOR-183503 |
| MAPK1 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 20630875 | SIGNOR-166686 |
| MAPK3 | phosphorylation up-regulates → | STMN1 PSer25 | phosphorylation down-regulates ⊣ | STMN1 | 9731215 | SIGNOR-249482 |
| CDK1 | phosphorylation up-regulates → | STMN1 PSer25 | phosphorylation up-regulates → | STMN1 | 8125092 | SIGNOR-279803 |
| MAPK8 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 20630875 | SIGNOR-166694 |
| PAK1 | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 14645234 | SIGNOR-119483 |
| MAPK3 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 9731215 | SIGNOR-249483 |
| MAPK13 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 8325880 | SIGNOR-25826 |
| PRKCB | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 9271428 | SIGNOR-50598 |
| CAMK2A | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 9686569 | SIGNOR-59354 |
| PRKCB | phosphorylation up-regulates → | STMN1 PSer25 | phosphorylation down-regulates ⊣ | STMN1 | 7637391 | SIGNOR-30353 |
| MAPK10 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 20630875 | SIGNOR-166690 |
| MAPK13 | phosphorylation up-regulates → | STMN1 PSer25 | phosphorylation down-regulates ⊣ | STMN1 | 8125092 | SIGNOR-36362 |
| PRKCB | phosphorylation up-regulates → | STMN1 PSer25 | phosphorylation down-regulates ⊣ | STMN1 | 9271428 | SIGNOR-50594 |
| CAMK2B | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 9686569 | SIGNOR-59358 |
| PRKACA | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 8376365 | SIGNOR-38318 |
| PRKACA | phosphorylation up-regulates → | STMN1 PSer63 | phosphorylation down-regulates ⊣ | STMN1 | 8125092 | SIGNOR-36374 |
| MAPK9 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 20630875 | SIGNOR-166698 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CAMK2A | phosphorylation down-regulates | STMN1 | SIGNOR-149640 |
| CDK1 | phosphorylation → up-regulates activity | STMN1 | SIGNOR-279802 |
| PAK4 | phosphorylation → down-regulates activity | STMN1 | SIGNOR-280058 |
| PRKACA | phosphorylation down-regulates | STMN1 | SIGNOR-38322 |
| MAPK13 | phosphorylation down-regulates | STMN1 | SIGNOR-37848 |
| CDK5 | phosphorylation down-regulates | STMN1 | SIGNOR-166682 |
| CAMK4 | phosphorylation down-regulates | STMN1 | SIGNOR-34743 |
| PRKCB | phosphorylation down-regulates | STMN1 | SIGNOR-30357 |
| UHMK1 | phosphorylation down-regulates | STMN1 | SIGNOR-182489 |
| PRKACA | phosphorylation down-regulates | STMN1 | SIGNOR-36370 |
| ERK1/2 | phosphorylation → down-regulates activity | STMN1 | SIGNOR-270182 |
| PAK1 | phosphorylation down-regulates | STMN1 | SIGNOR-79955 |
| PAK1 | phosphorylation down-regulates | STMN1 | SIGNOR-183503 |
| MAPK1 | phosphorylation down-regulates | STMN1 | SIGNOR-166686 |
| MAPK3 | phosphorylation → down-regulates activity | STMN1 | SIGNOR-249482 |
| CDK1 | phosphorylation → up-regulates activity | STMN1 | SIGNOR-279803 |
| MAPK8 | phosphorylation down-regulates | STMN1 | SIGNOR-166694 |
| PAK1 | phosphorylation down-regulates | STMN1 | SIGNOR-119483 |
| MAPK3 | phosphorylation → down-regulates activity | STMN1 | SIGNOR-249483 |
| Gbeta | phosphorylation → down-regulates activity | STMN1 | SIGNOR-270082 |
| MAPK13 | phosphorylation down-regulates | STMN1 | SIGNOR-25826 |
| PRKCB | phosphorylation down-regulates | STMN1 | SIGNOR-50598 |
| CAMK2A | phosphorylation down-regulates | STMN1 | SIGNOR-59354 |
| PRKCB | phosphorylation down-regulates | STMN1 | SIGNOR-30353 |
| MAPK10 | phosphorylation down-regulates | STMN1 | SIGNOR-166690 |
| MAPK13 | phosphorylation down-regulates | STMN1 | SIGNOR-36362 |
| PRKCB | phosphorylation down-regulates | STMN1 | SIGNOR-50594 |
| CAMK2B | phosphorylation down-regulates | STMN1 | SIGNOR-59358 |
| PRKACA | phosphorylation down-regulates | STMN1 | SIGNOR-38318 |
| PRKACA | phosphorylation down-regulates | STMN1 | SIGNOR-36374 |
| AURKA | phosphorylation → down-regulates activity | STMN1 | SIGNOR-278913 |
| JNK | phosphorylation down-regulates | STMN1 | SIGNOR-269982 |
| MAPK9 | phosphorylation down-regulates | STMN1 | SIGNOR-166698 |