Entity Details

Name	UBTF_Ser389
ID	P17480
Role	residue
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Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CyclinA2/CDK2	UBTF	Ser389 View in OncoXplorer	INKKQATsPASKKPA	phosphorylation up-regulates	11698641	SIGNOR-217304
CyclinE/CDK2	UBTF	Ser389 View in OncoXplorer	INKKQATsPASKKPA	phosphorylation up-regulates	11698641	SIGNOR-216678
CDK2	UBTF	Ser389 View in OncoXplorer	INKKQATsPASKKPA	phosphorylation up-regulates activity	11698641	SIGNOR-235419

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CyclinA2/CDK2	phosphorylation up-regulates →	UBTF PSer389	phosphorylation up-regulates →	UBTF	11698641	SIGNOR-217304
CyclinE/CDK2	phosphorylation up-regulates →	UBTF PSer389	phosphorylation up-regulates →	UBTF	11698641	SIGNOR-216678
CDK2	phosphorylation up-regulates →	UBTF PSer389	phosphorylation up-regulates →	UBTF	11698641	SIGNOR-235419

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CyclinA2/CDK2	phosphorylation → up-regulates	UBTF	SIGNOR-217304
CyclinE/CDK2	phosphorylation → up-regulates	UBTF	SIGNOR-216678
CDK2	phosphorylation → up-regulates activity	UBTF	SIGNOR-235419