Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPK3	TAL1	Ser122 View in OncoXplorer	DGRMVQLsPPALAAP	phosphorylation down-regulates	11904294	SIGNOR-116153
PRKACA	TAL1	Ser122 View in OncoXplorer	DGRMVQLsPPALAAP	phosphorylation down-regulates	22310283	SIGNOR-195987
MAP2K1	TAL1	Ser122 View in OncoXplorer	DGRMVQLsPPALAAP	phosphorylation down-regulates	11904294	SIGNOR-116149
AKT	TAL1	Thr90	EARHRVPtTELCRPP	phosphorylation down-regulates	15930267	SIGNOR-137942
PRKACA	TAL1	Ser172	NRVKRRPsPYEMEIT	phosphorylation up-regulates	22310283	SIGNOR-195983
MEK1/2	TAL1	Ser122 View in OncoXplorer	DGRMVQLsPPALAAP	phosphorylation down-regulates	11904294	SIGNOR-244975
AKT1	TAL1	Thr90	EARHRVPtTELCRPP	phosphorylation down-regulates	15930267	SIGNOR-252479

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK3	phosphorylation up-regulates →	TAL1 PSer122	phosphorylation down-regulates ⊣	TAL1	11904294	SIGNOR-116153
PRKACA	phosphorylation up-regulates →	TAL1 PSer122	phosphorylation down-regulates ⊣	TAL1	22310283	SIGNOR-195987
MAP2K1	phosphorylation up-regulates →	TAL1 PSer122	phosphorylation down-regulates ⊣	TAL1	11904294	SIGNOR-116149
AKT	phosphorylation up-regulates →	TAL1 PThr90	phosphorylation down-regulates ⊣	TAL1	15930267	SIGNOR-137942
PRKACA	phosphorylation up-regulates →	TAL1 PSer172	phosphorylation up-regulates →	TAL1	22310283	SIGNOR-195983
MEK1/2	phosphorylation up-regulates →	TAL1 PSer122	phosphorylation down-regulates ⊣	TAL1	11904294	SIGNOR-244975
AKT1	phosphorylation up-regulates →	TAL1 PThr90	phosphorylation down-regulates ⊣	TAL1	15930267	SIGNOR-252479

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPK3	phosphorylation down-regulates	TAL1	SIGNOR-116153
PRKACA	phosphorylation down-regulates	TAL1	SIGNOR-195987
MAP2K1	phosphorylation down-regulates	TAL1	SIGNOR-116149
AKT	phosphorylation down-regulates	TAL1	SIGNOR-137942
PRKACA	phosphorylation → up-regulates	TAL1	SIGNOR-195983
MEK1/2	phosphorylation down-regulates	TAL1	SIGNOR-244975
AKT1	phosphorylation down-regulates	TAL1	SIGNOR-252479