Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PAK1	SYN1	Ser605 View in OncoXplorer	AGPTRQAsQAGPVPR	phosphorylation up-regulates activity	12237306	SIGNOR-250235
CAMK1	SYN1	Ser9 View in OncoXplorer	NYLRRRLsDSNFMAN	phosphorylation down-regulates activity	10571231	SIGNOR-250615
PRKACA	SYN1	Ser9 View in OncoXplorer	NYLRRRLsDSNFMAN	phosphorylation down-regulates activity	10571231	SIGNOR-250058
CAMK2G	SYN1	Ser605 View in OncoXplorer	AGPTRQAsQAGPVPR	phosphorylation unknown	3118371	SIGNOR-250708
PKA	SYN1	–		phosphorylation down-regulates activity	10571231	SIGNOR-264108
CAMK2G	SYN1	Ser568 View in OncoXplorer	PQATRQTsVSGPAPP	phosphorylation unknown	3118371	SIGNOR-250707
CDK5	SYN1	Ser551 View in OncoXplorer	PAARPPAsPSPQRQA	phosphorylation up-regulates	10880969	SIGNOR-78883
PAK	SYN1	–		phosphorylation unknown	12237306	SIGNOR-269974
PAK3	SYN1	Ser605 View in OncoXplorer	AGPTRQAsQAGPVPR	phosphorylation up-regulates activity	12237306	SIGNOR-250246
PRKAA1	SYN1	Ser9 View in OncoXplorer	NYLRRRLsDSNFMAN	phosphorylation down-regulates activity	10880969	SIGNOR-78891
CDK5	SYN1	Ser553 View in OncoXplorer	ARPPASPsPQRQAGP	phosphorylation up-regulates	10880969	SIGNOR-78887
UHMK1	SYN1	Ser438 View in OncoXplorer	GSHGQTPsPGALPLG	phosphorylation unknown	10880969	SIGNOR-78899
PAK2	SYN1	Ser9 View in OncoXplorer	NYLRRRLsDSNFMAN	phosphorylation unknown	12237306	SIGNOR-250236

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PAK1	phosphorylation up-regulates →	SYN1 PSer605	phosphorylation up-regulates →	SYN1	12237306	SIGNOR-250235
CAMK1	phosphorylation up-regulates →	SYN1 PSer9	phosphorylation down-regulates ⊣	SYN1	10571231	SIGNOR-250615
PRKACA	phosphorylation up-regulates →	SYN1 PSer9	phosphorylation down-regulates ⊣	SYN1	10571231	SIGNOR-250058
CAMK2G	phosphorylation up-regulates →	SYN1 PSer605	phosphorylation down-regulates ⊣	SYN1	3118371	SIGNOR-250708
CAMK2G	phosphorylation up-regulates →	SYN1 PSer568	phosphorylation down-regulates ⊣	SYN1	3118371	SIGNOR-250707
CDK5	phosphorylation up-regulates →	SYN1 PSer551	phosphorylation up-regulates →	SYN1	10880969	SIGNOR-78883
PAK3	phosphorylation up-regulates →	SYN1 PSer605	phosphorylation up-regulates →	SYN1	12237306	SIGNOR-250246
PRKAA1	phosphorylation up-regulates →	SYN1 PSer9	phosphorylation down-regulates ⊣	SYN1	10880969	SIGNOR-78891
CDK5	phosphorylation up-regulates →	SYN1 PSer553	phosphorylation up-regulates →	SYN1	10880969	SIGNOR-78887
UHMK1	phosphorylation up-regulates →	SYN1 PSer438	phosphorylation down-regulates ⊣	SYN1	10880969	SIGNOR-78899
PAK2	phosphorylation up-regulates →	SYN1 PSer9	phosphorylation down-regulates ⊣	SYN1	12237306	SIGNOR-250236

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PAK1	phosphorylation → up-regulates activity	SYN1	SIGNOR-250235
CAMK1	phosphorylation → down-regulates activity	SYN1	SIGNOR-250615
PRKACA	phosphorylation → down-regulates activity	SYN1	SIGNOR-250058
CAMK2G	phosphorylation → unknown	SYN1	SIGNOR-250708
PKA	phosphorylation → down-regulates activity	SYN1	SIGNOR-264108
CAMK2G	phosphorylation → unknown	SYN1	SIGNOR-250707
CDK5	phosphorylation → up-regulates	SYN1	SIGNOR-78883
PAK	phosphorylation → unknown	SYN1	SIGNOR-269974
PAK3	phosphorylation → up-regulates activity	SYN1	SIGNOR-250246
PRKAA1	phosphorylation → down-regulates activity	SYN1	SIGNOR-78891
CDK5	phosphorylation → up-regulates	SYN1	SIGNOR-78887
UHMK1	phosphorylation → unknown	SYN1	SIGNOR-78899
PAK2	phosphorylation → unknown	SYN1	SIGNOR-250236