| Name | PTPN2 |
| ID | P17706 |
| Role | substrate |
| Enzymatic Domains |
Tyrosine-protein phosphatase 5-275 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | PTPN2 | Ser304 | LSPAFDHsPNKIMTE | phosphorylation unknown | 15030318 | SIGNOR-123471 |
| CDK1 | PTPN2 | Ser304 | LSPAFDHsPNKIMTE | phosphorylation unknown | 15030318 | SIGNOR-123467 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | PTPN2 PSer304 | phosphorylation down-regulates ⊣ | PTPN2 | 15030318 | SIGNOR-123471 |
| CDK1 | phosphorylation up-regulates → | PTPN2 PSer304 | phosphorylation down-regulates ⊣ | PTPN2 | 15030318 | SIGNOR-123467 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation → unknown | PTPN2 | SIGNOR-123471 |
| CDK1 | phosphorylation → unknown | PTPN2 | SIGNOR-123467 |