Entity Details

Name DDX5
ID P17844
Role substrate
Enzymatic Domains
Helicase ATP-binding 125-300
PROSITE-ProRule
Helicase C-terminal 328-475
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ABL1DDX5Tyr593NGMNQQAyAYPATAAphosphorylation
up-regulates		17018282SIGNOR-149988
PRKCADDX5Ser557VSAGIQTsFRTGNPTphosphorylation
down-regulates activity		7525583SIGNOR-248896
PAK5DDX5Thr69HPDLARRtAQEVETYphosphorylation
up-regulates quantity by stabilization		34936874SIGNOR-275658
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ABL1phosphorylation
up-regulates
→
DDX5
PTyr593		phosphorylation
up-regulates
→		DDX517018282SIGNOR-149988
PRKCAphosphorylation
up-regulates
→
DDX5
PSer557		phosphorylation
down-regulates
⊣		DDX57525583SIGNOR-248896
PAK5phosphorylation
up-regulates
→
DDX5
PThr69		phosphorylation
up-regulates
→		DDX534936874SIGNOR-275658
Regulator Mechanism/Effect Target SIGNOR-ID
ABL1phosphorylation
→
up-regulates 		DDX5SIGNOR-149988
PRKCAphosphorylation
→
down-regulates activity 		DDX5SIGNOR-248896
PAK5phosphorylation
→
up-regulates quantity by stabilization 		DDX5SIGNOR-275658