Entity Details

Name PTPN1_Tyr152
ID P18031
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
INSRPTPN1Tyr152ISEDIKSyYTVRQLEphosphorylation
up-regulates activity		11506178SIGNOR-249368
PTPN1PTPN1Tyr152ISEDIKSyYTVRQLEdephosphorylation
down-regulates activity		11506178SIGNOR-248424
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
INSRphosphorylation
up-regulates
→
PTPN1
PTyr152		phosphorylation
up-regulates
→		PTPN111506178SIGNOR-249368
PTPN1dephosphorylation
down-regulates
⊣
PTPN1
PTyr152		dephosphorylation
up-regulates
→		PTPN111506178SIGNOR-248424
Regulator Mechanism/Effect Target SIGNOR-ID
INSRphosphorylation
→
up-regulates activity 		PTPN1SIGNOR-249368
PTPN1dephosphorylation
→
down-regulates activity 		PTPN1SIGNOR-248424