Entity Details

Name PTPN1_Tyr153
ID P18031
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN1PTPN1Tyr153SEDIKSYyTVRQLELdephosphorylation
down-regulates activity		11506178SIGNOR-248425
INSRPTPN1Tyr153SEDIKSYyTVRQLELphosphorylation
up-regulates activity		11506178SIGNOR-249369
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN1dephosphorylation
down-regulates
⊣
PTPN1
PTyr153		dephosphorylation
up-regulates
→		PTPN111506178SIGNOR-248425
INSRphosphorylation
up-regulates
→
PTPN1
PTyr153		phosphorylation
up-regulates
→		PTPN111506178SIGNOR-249369
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN1dephosphorylation
→
down-regulates activity 		PTPN1SIGNOR-248425
INSRphosphorylation
→
up-regulates activity 		PTPN1SIGNOR-249369