Entity Details

Name VCL
ID P18206
Role substrate
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCAVCLSer1101NAQNLMQsVKETVREphosphorylation
unknown
11741957SIGNOR-249128
PTPRGVCLTyr822 KSFLDSGyRILGAVAdephosphorylation
down-regulates activity
25624455SIGNOR-254731
ABL1VCLTyr822 KSFLDSGyRILGAVAphosphorylation
up-regulates activity
24751539SIGNOR-278464
SRCVCLTyr100QMLQSDPySVPARDYphosphorylation
down-regulates activity
15229287SIGNOR-247424
PRKCAVCLSer1113VREAEAAsIKIRTDAphosphorylation
unknown
11741957SIGNOR-249129
SRCVCLTyr1133WVRKTPWyQphosphorylation
down-regulates activity
15229287SIGNOR-247428
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCAphosphorylation
up-regulates
→
VCL
PSer1101
phosphorylation
down-regulates
⊣
VCL11741957SIGNOR-249128
PTPRGdephosphorylation
down-regulates
⊣
VCL
PTyr822
dephosphorylation
up-regulates
→
VCL25624455SIGNOR-254731
ABL1phosphorylation
up-regulates
→
VCL
PTyr822
phosphorylation
up-regulates
→
VCL24751539SIGNOR-278464
SRCphosphorylation
up-regulates
→
VCL
PTyr100
phosphorylation
down-regulates
⊣
VCL15229287SIGNOR-247424
PRKCAphosphorylation
up-regulates
→
VCL
PSer1113
phosphorylation
down-regulates
⊣
VCL11741957SIGNOR-249129
SRCphosphorylation
up-regulates
→
VCL
PTyr1133
phosphorylation
down-regulates
⊣
VCL15229287SIGNOR-247428
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCAphosphorylation
→
unknown
VCLSIGNOR-249128
PTPRGdephosphorylation
→
down-regulates activity
VCLSIGNOR-254731
ABL1phosphorylation
→
up-regulates activity
VCLSIGNOR-278464
SRCphosphorylation
→
down-regulates activity
VCLSIGNOR-247424
PRKCAphosphorylation
→
unknown
VCLSIGNOR-249129
SRCphosphorylation
→
down-regulates activity
VCLSIGNOR-247428