Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
SRC	VCL	Tyr100	QMLQSDPySVPARDY	phosphorylation down-regulates activity	15229287	SIGNOR-247424
SRC	VCL	Tyr1133	WVRKTPWyQ	phosphorylation down-regulates activity	15229287	SIGNOR-247428
PTPRG	VCL	Tyr822 View in OncoXplorer	KSFLDSGyRILGAVA	dephosphorylation down-regulates activity	25624455	SIGNOR-254731
ABL1	VCL	Tyr822 View in OncoXplorer	KSFLDSGyRILGAVA	phosphorylation up-regulates activity	24751539	SIGNOR-278464
PRKCA	VCL	Ser1113	VREAEAAsIKIRTDA	phosphorylation unknown	11741957	SIGNOR-249129
PRKCA	VCL	Ser1101	NAQNLMQsVKETVRE	phosphorylation unknown	11741957	SIGNOR-249128

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
SRC	phosphorylation up-regulates →	VCL PTyr100	phosphorylation down-regulates ⊣	VCL	15229287	SIGNOR-247424
SRC	phosphorylation up-regulates →	VCL PTyr1133	phosphorylation down-regulates ⊣	VCL	15229287	SIGNOR-247428
PTPRG	dephosphorylation down-regulates ⊣	VCL PTyr822	dephosphorylation up-regulates →	VCL	25624455	SIGNOR-254731
ABL1	phosphorylation up-regulates →	VCL PTyr822	phosphorylation up-regulates →	VCL	24751539	SIGNOR-278464
PRKCA	phosphorylation up-regulates →	VCL PSer1113	phosphorylation down-regulates ⊣	VCL	11741957	SIGNOR-249129
PRKCA	phosphorylation up-regulates →	VCL PSer1101	phosphorylation down-regulates ⊣	VCL	11741957	SIGNOR-249128

Regulator	Mechanism/Effect	Target	SIGNOR-ID
SRC	phosphorylation → down-regulates activity	VCL	SIGNOR-247424
SRC	phosphorylation → down-regulates activity	VCL	SIGNOR-247428
PTPRG	dephosphorylation → down-regulates activity	VCL	SIGNOR-254731
ABL1	phosphorylation → up-regulates activity	VCL	SIGNOR-278464
PRKCA	phosphorylation → unknown	VCL	SIGNOR-249129
PRKCA	phosphorylation → unknown	VCL	SIGNOR-249128