| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKN1 | PGAM1 | Ser23 | WNLENRFsGWYDADL | phosphorylation down-regulates | 12189148 | SIGNOR-91606 |
| PKN1 | PGAM1 | Ser118 | QVKIWRRsYDVPPPP | phosphorylation down-regulates | 12189148 | SIGNOR-91602 |
| PAK1 | PGAM1 | Ser23 | WNLENRFsGWYDADL | phosphorylation down-regulates | 12189148 | SIGNOR-91598 |
| FGFR1 | PGAM1 | – | phosphorylation up-regulates activity | 23653202 | SIGNOR-279175 | |
| PAK1 | PGAM1 | Ser118 | QVKIWRRsYDVPPPP | phosphorylation down-regulates | 12189148 | SIGNOR-91594 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKN1 | phosphorylation up-regulates → | PGAM1 PSer23 | phosphorylation down-regulates ⊣ | PGAM1 | 12189148 | SIGNOR-91606 |
| PKN1 | phosphorylation up-regulates → | PGAM1 PSer118 | phosphorylation down-regulates ⊣ | PGAM1 | 12189148 | SIGNOR-91602 |
| PAK1 | phosphorylation up-regulates → | PGAM1 PSer23 | phosphorylation down-regulates ⊣ | PGAM1 | 12189148 | SIGNOR-91598 |
| PAK1 | phosphorylation up-regulates → | PGAM1 PSer118 | phosphorylation down-regulates ⊣ | PGAM1 | 12189148 | SIGNOR-91594 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PKN1 | phosphorylation down-regulates | PGAM1 | SIGNOR-91606 |
| PKN1 | phosphorylation down-regulates | PGAM1 | SIGNOR-91602 |
| PAK1 | phosphorylation down-regulates | PGAM1 | SIGNOR-91598 |
| FGFR1 | phosphorylation → up-regulates activity | PGAM1 | SIGNOR-279175 |
| PAK1 | phosphorylation down-regulates | PGAM1 | SIGNOR-91594 |
