Entity Details

Name	RCC1
ID	P18754
Role	substrate
Enzymatic Domains
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Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
STK3	RCC1	Ser2	sPKRIAKR	phosphorylation up-regulates	19559616	SIGNOR-263146
CDK1	RCC1	Ser11 View in OncoXplorer	KRIAKRRsPPADAIP	phosphorylation up-regulates activity	15014043	SIGNOR-262702
CDK1	RCC1	Thr274	SNYHQLGtPGTESCF	phosphorylation up-regulates activity	15014043	SIGNOR-262704
CDK1	RCC1	Ser387	GQDEDAWsPVEMMGK	phosphorylation up-regulates activity	15014043	SIGNOR-262703
STK3	RCC1	Ser11 View in OncoXplorer	KRIAKRRsPPADAIP	phosphorylation up-regulates	19559616	SIGNOR-263145
CDK1	RCC1	Ser2	sPKRIAKR	phosphorylation up-regulates activity	15014043	SIGNOR-262701

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
STK3	phosphorylation up-regulates →	RCC1 PSer2	phosphorylation up-regulates →	RCC1	19559616	SIGNOR-263146
CDK1	phosphorylation up-regulates →	RCC1 PSer11	phosphorylation up-regulates →	RCC1	15014043	SIGNOR-262702
CDK1	phosphorylation up-regulates →	RCC1 PThr274	phosphorylation up-regulates →	RCC1	15014043	SIGNOR-262704
CDK1	phosphorylation up-regulates →	RCC1 PSer387	phosphorylation up-regulates →	RCC1	15014043	SIGNOR-262703
STK3	phosphorylation up-regulates →	RCC1 PSer11	phosphorylation up-regulates →	RCC1	19559616	SIGNOR-263145
CDK1	phosphorylation up-regulates →	RCC1 PSer2	phosphorylation up-regulates →	RCC1	15014043	SIGNOR-262701

Regulator	Mechanism/Effect	Target	SIGNOR-ID
STK3	phosphorylation → up-regulates	RCC1	SIGNOR-263146
CDK1	phosphorylation → up-regulates activity	RCC1	SIGNOR-262702
CDK1	phosphorylation → up-regulates activity	RCC1	SIGNOR-262704
CDK1	phosphorylation → up-regulates activity	RCC1	SIGNOR-262703
STK3	phosphorylation → up-regulates	RCC1	SIGNOR-263145
CDK1	phosphorylation → up-regulates activity	RCC1	SIGNOR-262701