| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | ATF4 | Ser215 | IKEEDTPsDNDSGIC | phosphorylation down-regulates quantity by destabilization | 23123191 | SIGNOR-276425 |
| CSNK2B | ATF4 | Ser215 | IKEEDTPsDNDSGIC | phosphorylation down-regulates quantity by destabilization | 23123191 | SIGNOR-276424 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | ATF4 PSer215 | phosphorylation down-regulates ⊣ | ATF4 | 23123191 | SIGNOR-276425 |
| CSNK2B | phosphorylation up-regulates → | ATF4 PSer215 | phosphorylation down-regulates ⊣ | ATF4 | 23123191 | SIGNOR-276424 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation![]() down-regulates quantity by destabilization | ATF4 | SIGNOR-276425 |
| CSNK2B | phosphorylation![]() down-regulates quantity by destabilization | ATF4 | SIGNOR-276424 |