| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A2 | XRCC1 | Thr523 | AGSTDENtDSEEHQE | phosphorylation up-regulates activity | 15367657 | SIGNOR-251052 |
| CSNK2A1 | XRCC1 | Thr523 | AGSTDENtDSEEHQE | phosphorylation up-regulates | 20471329 | SIGNOR-165435 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A2 | phosphorylation up-regulates → | XRCC1 PThr523 | phosphorylation up-regulates → | XRCC1 | 15367657 | SIGNOR-251052 |
| CSNK2A1 | phosphorylation up-regulates → | XRCC1 PThr523 | phosphorylation up-regulates → | XRCC1 | 20471329 | SIGNOR-165435 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A2 | phosphorylation → up-regulates activity | XRCC1 | SIGNOR-251052 |
| CSNK2A1 | phosphorylation → up-regulates | XRCC1 | SIGNOR-165435 |
