| Name | CDH2 |
| ID | P19022 |
| Role | substrate |
| Enzymatic Domains |
Cadherin 1 160-267 PROSITE-ProRule
Cadherin 2 268-382 PROSITE-ProRule
Cadherin 3 383-497 PROSITE-ProRule
Cadherin 4 498-603 PROSITE-ProRule
Cadherin 5 604-714 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | CDH2 | Tyr860 | DSLLVFDyEGSGSTA | phosphorylation down-regulates | 16371504 | SIGNOR-143238 |
| SRC | CDH2 | Tyr884 | SSGGEQDyDYLNDWG | phosphorylation down-regulates | 16371504 | SIGNOR-143242 |
| SRC | CDH2 | Tyr886 | GGEQDYDyLNDWGPR | phosphorylation down-regulates | 16371504 | SIGNOR-143246 |
| SRC | CDH2 | Tyr852 | NDPTAPPyDSLLVFD | phosphorylation down-regulates | 16371504 | SIGNOR-143234 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | CDH2 PTyr860 | phosphorylation down-regulates ⊣ | CDH2 | 16371504 | SIGNOR-143238 |
| SRC | phosphorylation up-regulates → | CDH2 PTyr884 | phosphorylation down-regulates ⊣ | CDH2 | 16371504 | SIGNOR-143242 |
| SRC | phosphorylation up-regulates → | CDH2 PTyr886 | phosphorylation down-regulates ⊣ | CDH2 | 16371504 | SIGNOR-143246 |
| SRC | phosphorylation up-regulates → | CDH2 PTyr852 | phosphorylation down-regulates ⊣ | CDH2 | 16371504 | SIGNOR-143234 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation down-regulates | CDH2 | SIGNOR-143238 |
| SRC | phosphorylation down-regulates | CDH2 | SIGNOR-143242 |
| SRC | phosphorylation down-regulates | CDH2 | SIGNOR-143246 |
| SRC | phosphorylation down-regulates | CDH2 | SIGNOR-143234 |