| Name | PLCG1 |
| ID | P19174 |
| Role | kinase |
| Enzymatic Domains |
PH 1 27-142 PROSITE-ProRule
EF-hand 152-187 PROSITE-ProRule
PI-PLC X-box 320-464 PROSITE-ProRule
PH 2; first part 489-523 PROSITE-ProRule
SH2 1 550-657 PROSITE-ProRule
SH2 2 668-756 PROSITE-ProRule
SH3 791-851 PROSITE-ProRule
PH 2; second part 895-931 PROSITE-ProRule
PI-PLC Y-box 953-1070 PROSITE-ProRule
C2 1071-1194 PROSITE-ProRule |
View in  |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLCG1 | PRKCA | – | phosphorylation up-regulates | 12645577 | SIGNOR-99310 | |
| PLCG1 | CDKN1A | Ser146 | GRKRRQTsMTDFYHS | phosphorylation up-regulates quantity by stabilization | 31575057 | SIGNOR-262962 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLCG1 | phosphorylation up-regulates → | CDKN1A PSer146 | phosphorylation up-regulates → | CDKN1A | 31575057 | SIGNOR-262962 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLCG1 | phosphorylation → up-regulates | PRKCA | SIGNOR-99310 |
| PLCG1 | phosphorylation → up-regulates quantity by stabilization | CDKN1A | SIGNOR-262962 |