Entity Details

Name PRKACA_Ser23
ID P19429
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCATNNI3Ser23PAPIRRRsSNYRAYAphosphorylation
up-regulates activity		11121119SIGNOR-249066
PRKCDTNNI3Ser23PAPIRRRsSNYRAYAphosphorylation
up-regulates activity		18550549SIGNOR-178880
PRKG1TNNI3Ser23PAPIRRRsSNYRAYAphosphorylation
up-regulates activity		15769444SIGNOR-134640
PRKACATNNI3Ser23PAPIRRRsSNYRAYAphosphorylation
up-regulates activity		15769444SIGNOR-134605
PPP2CATNNI3Ser23PAPIRRRsSNYRAYAdephosphorylation
down-regulates		15769444SIGNOR-134597
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCAphosphorylation
up-regulates
→
TNNI3
PSer23		phosphorylation
up-regulates
→		TNNI311121119SIGNOR-249066
PRKCDphosphorylation
up-regulates
→
TNNI3
PSer23		phosphorylation
up-regulates
→		TNNI318550549SIGNOR-178880
PRKG1phosphorylation
up-regulates
→
TNNI3
PSer23		phosphorylation
up-regulates
→		TNNI315769444SIGNOR-134640
PRKACAphosphorylation
up-regulates
→
TNNI3
PSer23		phosphorylation
up-regulates
→		TNNI315769444SIGNOR-134605
PPP2CAdephosphorylation
down-regulates
⊣
TNNI3
PSer23		dephosphorylation
up-regulates
→		TNNI315769444SIGNOR-134597
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCAphosphorylation
→
up-regulates activity 		TNNI3SIGNOR-249066
PRKCDphosphorylation
→
up-regulates activity 		TNNI3SIGNOR-178880
PRKG1phosphorylation
→
up-regulates activity 		TNNI3SIGNOR-134640
PRKACAphosphorylation
→
up-regulates activity 		TNNI3SIGNOR-134605
PPP2CAdephosphorylation
img/direct_inhibition.png
down-regulates 		TNNI3SIGNOR-134597