Entity Details

Name PRKACA_Ser24
ID P19429
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKG1TNNI3Ser24APIRRRSsNYRAYATphosphorylation
up-regulates activity		15769444SIGNOR-134644
PRKCATNNI3Ser24APIRRRSsNYRAYATphosphorylation
up-regulates activity		11121119SIGNOR-249067
PRKACATNNI3Ser24APIRRRSsNYRAYATphosphorylation
up-regulates activity		15769444SIGNOR-134609
PRKCDTNNI3Ser24APIRRRSsNYRAYATphosphorylation
up-regulates activity		18550549SIGNOR-178884
PPP2CATNNI3Ser24APIRRRSsNYRAYATdephosphorylation
down-regulates		15769444SIGNOR-134601
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKG1phosphorylation
up-regulates
→
TNNI3
PSer24		phosphorylation
up-regulates
→		TNNI315769444SIGNOR-134644
PRKCAphosphorylation
up-regulates
→
TNNI3
PSer24		phosphorylation
up-regulates
→		TNNI311121119SIGNOR-249067
PRKACAphosphorylation
up-regulates
→
TNNI3
PSer24		phosphorylation
up-regulates
→		TNNI315769444SIGNOR-134609
PRKCDphosphorylation
up-regulates
→
TNNI3
PSer24		phosphorylation
up-regulates
→		TNNI318550549SIGNOR-178884
PPP2CAdephosphorylation
down-regulates
⊣
TNNI3
PSer24		dephosphorylation
up-regulates
→		TNNI315769444SIGNOR-134601
Regulator Mechanism/Effect Target SIGNOR-ID
PRKG1phosphorylation
→
up-regulates activity 		TNNI3SIGNOR-134644
PRKCAphosphorylation
→
up-regulates activity 		TNNI3SIGNOR-249067
PRKACAphosphorylation
→
up-regulates activity 		TNNI3SIGNOR-134609
PRKCDphosphorylation
→
up-regulates activity 		TNNI3SIGNOR-178884
PPP2CAdephosphorylation
img/direct_inhibition.png
down-regulates 		TNNI3SIGNOR-134601